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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APLF
All Species:
3.33
Human Site:
T362
Identified Species:
9.17
UniProt:
Q8IW19
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IW19
NP_775816.1
511
56956
T362
E
T
L
H
A
K
A
T
D
S
V
L
Q
G
S
Chimpanzee
Pan troglodytes
XP_515525
303
34195
K180
Y
G
A
N
C
Y
R
K
N
P
V
H
F
Q
H
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_538525
510
57035
T360
E
T
L
S
A
K
T
T
D
S
A
A
Q
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D842
499
54950
A357
D
A
L
H
T
D
T
A
D
P
V
L
G
C
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514287
555
61656
N404
E
A
S
S
S
A
P
N
R
T
V
P
Q
S
V
Chicken
Gallus gallus
XP_419335
514
57457
V364
E
I
S
Y
T
T
K
V
A
E
A
S
E
G
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001099159
262
29285
L139
S
S
C
T
H
S
N
L
R
H
T
H
A
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A8JR14
255
27987
R132
F
G
I
R
C
Y
R
R
N
P
A
H
R
S
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788055
674
74378
D507
S
D
E
D
D
D
D
D
E
A
P
K
K
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.9
N.A.
72.2
N.A.
60
N.A.
N.A.
41.2
44.7
N.A.
23.4
N.A.
21.3
N.A.
N.A.
28.1
Protein Similarity:
100
58.9
N.A.
81.4
N.A.
74.7
N.A.
N.A.
57.2
61.8
N.A.
33
N.A.
31.5
N.A.
N.A.
43.7
P-Site Identity:
100
6.6
N.A.
73.3
N.A.
40
N.A.
N.A.
20
20
N.A.
0
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
20
N.A.
73.3
N.A.
46.6
N.A.
N.A.
33.3
33.3
N.A.
6.6
N.A.
26.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
23
12
0
23
12
12
12
12
12
34
12
12
0
12
% A
% Cys:
0
0
12
0
23
0
0
0
0
0
0
0
0
12
0
% C
% Asp:
12
12
0
12
12
23
12
12
34
0
0
0
0
0
12
% D
% Glu:
45
0
12
0
0
0
0
0
12
12
0
0
12
12
0
% E
% Phe:
12
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
0
23
0
0
0
0
0
0
0
0
0
0
12
34
0
% G
% His:
0
0
0
23
12
0
0
0
0
12
0
34
0
0
12
% H
% Ile:
0
12
12
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
23
12
12
0
0
0
12
12
12
0
% K
% Leu:
0
0
34
0
0
0
0
12
0
0
0
23
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
0
0
12
12
23
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
12
0
0
34
12
12
0
0
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
34
12
0
% Q
% Arg:
0
0
0
12
0
0
23
12
23
0
0
0
12
0
0
% R
% Ser:
23
12
23
23
12
12
0
0
0
23
0
12
0
23
45
% S
% Thr:
0
23
0
12
23
12
23
23
0
12
12
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
12
0
0
45
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
0
12
0
23
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _